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All-in-One Scalp Shampoo

Onescalp is an all-in-one shampoo that helps balances sebum levels in the scalp and has anti-fungal and anti-dandruff properties. It is specially designed to be compatible with other hair loss treatments.

Dandruff

It is normal to shed some skin on the scalp, as anywhere else on the body. These small skin cells are shed continuously and we do not notice them.

Dandruff occurs when the process of skin renewal speeds up, so a greater number of dead skin cells are being shed. These cells are also shed in larger clumps which, because they can be seen with the naked eye, can become embarrassing. The scalp may also become itchy in cases of dandruff.

These are all a symptom of commonly caused by a yeast build up, as well as genetic, environmental, hormonal and immune-system factors.

Fungus

Malassezia furfur is a lipophilic fungus which lives in the skin. Its growth is dependent on the sebum secretions in the skin. Malassezia furfur has also been proven as one of the causes of dandruff.

High levels of sebum can cause Malassezia furfur to proliferate in the scalp, causing irritation. In turn the body reacts to this irritation by speeding up the cell renewal process, which in turn generates more dandruff.

The Barrier Function

Irritation of the scalp causes hyperproliferation of keratinocytes
(skin cells).

This decreases the time taken for the keratinocytes to travel between the
basal layer (where they are formed)
and the stratum corneum
(the outermost layers of skin),
where they become corneocytes.

The resulting corneocytes are not
fully formed and are shed in clumps (dandruff), pushed out by further keratinocytes making their way to
the surface.

This whole process compromises
the barrier function of the skin cells, allowing moisture to escape the skin
and bacteria to be introduced.

The perturbations in the epidermal barrier not only cause further irritation and dandruff, but can also activate certain skin diseases, like psoriasis.

Onescalp’s anti-fungal properties

Onescalp’s active ingredient can inhibit the growth of the fungus Malassezia furfur.

Onescalp can also reduce seborrhoeic dermatitis, as well as the symptoms, namely the flaking and itchy, inflamed skin.

Nanogen Onescalp contains no alcohol as it is specifically formulated to improve the scalp health of hair loss sufferers.

Restoring the barrier function

Involucrin is a terminal marker of keratinocyte differentiation.

It has been shown to stimulate the formation of the corneal envelope, strengthening and protecting the barriers of the skin.

Nanogen’s Onescalp could stimulate the synthesis of involucrin, shown in these pictures, the more active the synthesis, the more fluorescent it becomes.

Involucrin is responsible for the terminal phase of keratinocyte differentiation, thereby ensuring the regulation of the formation of the barrier function, shown below.

The corneocytes shown here are fully formed, locking the moisture into the scalp and protecting it from dryness (dandruff), bacteria introduction and skin diseases.

Frequently Asked Questions

• How often should I use Onescalp?
• You can use Onescalp as your shampoo every time you wash your hair.
  
  
• Can I use Onescalp with Nanoguard A?
• You should only wash your hair with one shampoo at a time, but if you wash your hair every day Onescalp is the ideal alternative to Nanoguard A
  (which you use every other day).
  
• 
  
• Does Onescalp interfere with any other treatments?
• Onescalp is safe to use with any other Hair Loss or Re-growth Treatment, including all Nanogen products, just make sure to rinse out the shampoo thoroughly, and allow your scalp to dry before applying any other treatment.

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